The CAS number of HEPBS is 161308-36-7, appearing as a white crystalline powder at 25 ºC. Its pKa value is 8.3, making it highly suitable for cell growth environments. This reagent-grade product creates a slightly turbid aqueous solution and should be prepared immediately before use. In analytical applications, when titrated with sodium hydroxide, it exhibits excellent UV characteristics.
HEPBS is a vital member of the piperazine buffer family. It is widely used to stabilize pH levels in cell culture media, providing the necessary acidic environment for growth. Furthermore, due to its compatibility with skin, it is utilized as a buffer in cosmetic raw materials to balance the alkalinity and acidity of various ingredients.


HEPBS provides strong buffering capacity within the pH range of 7.6 to 9.0. It features a stable chemical structure with an inactive piperazine ring that does not interfere with enzyme activity or react with most metals. This makes it a reliable choice for sensitive biochemical systems, provided that temperature fluctuations are considered during use.
| Assay Percent Range | 99% |
| Formula Weight | 266.36 |
| Physical Form | Crystalline Powder |
| Purity | ≥99% |
| pH (at 25ºC) | 8.3 |
| Packaging | Bottle |
Standard packaging options include 500g/bottle (plastic) or 25kg/bucket (cardboard), ensuring safe storage and transport.


We provide a wide array of industrial-grade biological buffering agents developed for diverse scientific and industrial applications. Our buffers are designed to maintain consistent pH levels even when acidic or alkaline components are introduced.

With years of experience in the biochemical industry, we specialize in the R&D and production of high-quality reagents, including blood collection tube additives, chemiluminescent reagents, and biological buffers. Our commitment to innovation and advanced production standards ensures the reliability of our products for research and clinical diagnostics.


